Tamoxifen 10 Sun Rise
Manufacturer: Sun Rise Substance: Tamoxifen citrate (Nolvadex) Pack: 10mg 10 pills
Tamoxifen 10 (Nolvadex) – a drug used to treat breast cancer, breast cancer, kidney cancer, melanoma and soft tissue sarcoma. Initially, this drug was developed exclusively for the treatment of women. It was used to prevent cancer. After all, he is able to detect and warn a person about the development of oncology, which made it possible to diagnose and cure a disease in time. But after a while, tamoxifen began to actively use in sports, in particular in bodybuilding. The effect of this drug is very slow, especially in the early stages of treatment, so it is recommended to take it along with other similar drugs.
Form of ussue
Nolvadex is presented in the form of tablets containing tamoxifen citrate (Brit. Pharm.) In an amount equivalent to 10 mg of tamoxifen.
Indications for use
Nolvadex is indicated for the treatment of breast cancer.
- Almost immediately after use, the drug increases the level of cholesterol in the blood. This significantly reduces the risk of heart disease. After all, as you know, many bodybuilding athletes can suffer from such diseases;
- Compared with other drugs, since tamoxifen is a very light estrogen, it does not harm the internal organs, but on the contrary, has a positive effect on the human body;
- Tamoxifen is much safer than other drugs. Even its long use does not bear special harm to the body.
Nolvadex (tamoxifen) is a nonsteroidal antiestrogen. In humans, Nolvadex acts primarily as an antiestrogen that inhibits the effects of endogenous estrogen, probably through binding to estrogen receptors. At the same time, clinical data indicate some favorable effect of the drug on RE-negative tumors, which suggests that there are other mechanisms of action. It is recognized that tamoxifen has estrogen-like effects on a number of body systems, including the endometrium, bones and blood lipids. After oral administration, Nolvadex is rapidly absorbed and maximum serum concentrations are reached within 4-7 hours.
Stable concentrations (approximately 300 ng / ml) are achieved after a four-week treatment with a daily intake of 40 mg. This drug binds well to serum albumin (> 99%). As a result of metabolism, in the process of hydroxylation, demethylation and conjugation, a number of metabolites are formed, having pharmacological profile similar to the initial chemical compound, thus contributing to the achievement of a therapeutic effect. Isolation occurs mainly through feces. The elimination half-life for the drug itself was determined to be about seven days, while for X-desmethyltamoxifene, the main circulating metabolite, was 14 days.