Megamentinc 625 Intas

Megamentinc (Augmentin) consists of Amonoxycilin and Klavulanova acid. Amonoxycilin is a semisynthetic antibiotic with a wide spectrum of action. Its antibacterial action is directed against many microorganisms. But the bacteria that synthesize the enzyme beta-lactamase, has a destructive effect on Amonoxycilin. Therefore, it has no effect on them. Due to the fact that the preparation contains Clavulanic acid, the protection of Amonoxycilin from degradation takes place. In this regard, we can safely assume that Augmentin is an extended-spectrum antibiotic. And has a destructive effect on very many microorganisms.

The Augmentin tablets dissolve very well in aqueous solutions. Take them preferably at the beginning of food intake. Distribution of the concentration of constituents of the substance in the preparation, in tissues and body fluids. Their location is observed in the gallbladder (bile), abdominal tissue, skin, fat and muscle tissue. The presence of concentration in the blood of the antibiotic is very small. Because the components of the drug are weakly bound to blood plasma proteins. Antibiotic can penetrate into breast milk.

It can also get to the fetus, through the placenta. But we want to reassure you that he will not do any harm. Studies have shown that women are also not worried about reproductive function. It is excreted from the body by an antibiotic, mainly through the kidneys with urine.

Pharmachologic effect

Antibiotic of a wide spectrum of action. Has bacteriolytic (destroying bacteria) action. It is active against a wide range of aerobic (developing only in the presence of oxygen) and anaerobic (able to exist in the absence of oxygen) gram-positive and aerobic gram-negative microorganisms, including strains producing beta-lactamase (enzyme that destroys penicillins). The clavulanic acid, which is part of the drug, ensures the stability of amoxicillin to the action of beta-lactamases, expanding the range of its action.

Contraindications

Hypersensitivity to the components of the drug. Intravenously should be used with caution in patients with severe impairment of liver function. When hives or erythematous rash appear, treatment should be discontinued. Use the drug during pregnancy (especially in the first trimester) and breast-feeding is not recommended. The drug should be administered with caution to patients with an indication of allergic reactions in the history (history of the disease).