Generic Zovirax Generic
Manufacturer: Generic Substance: Acyclovir (Zovirax) Pack: 5% Cream tube
Zovirax by Generic is an antiviral drug – a synthetic analogue of thymidine nucleoside. In infected cells containing viral thymidine kinase, phosphorylation and conversion to acyclovir monophosphate occurs. Under the influence of guanylyl cyclase acyclovir, monophosphate is converted to diphosphate and under the influence of several cellular enzymes – into triphosphate. High selectivity of action and low toxicity for humans are due to the lack of the necessary enzyme for the formation of acyclovir triphosphate in intact cells of the macroorganism. Acyclovir triphosphate, “embedded” in the DNA synthesized by the virus, blocks the multiplication of the virus.
The specificity and very high selectivity of the action of Zovirax are also due to its predominant accumulation in cells infected with the herpes virus. Highly active against Herpes simplex virus type 1 and type 2; A virus that causes varicella and herpes zoster (Varicella zoster); Of the Epstein-Barr virus (the types of viruses are indicated in order of increasing magnitude of the Zovirax IPC). Moderately active against CMV.
With herpes, Zovirax prevents the formation of new elements of the rash, reduces the likelihood of cutaneous dissemination and visceral complications, accelerates the formation of crusts, reduces pain in the acute phase of herpes zoster. Treatment with Zovirax has an immunostimulating effect.
Dosing and Administration
- Outwardly. Cream or ointment Zovirax is applied to the affected areas 4-6 times a day (as soon as possible after the onset of infection). It is important to begin treatment of a recurrent infection during the prodromal phase or at the very beginning of the infection. Duration of treatment – at least 5 days, a maximum of 10 days.
- Locally. Eye ointment is squeezed out by a tape 1 cm long and placed in the lower conjunctival sac 5 times a day (every 4 hours). Treatment with Zovirax continues for at least 3 days after healing.
- Local reactions: sometimes – short-term redness, itching, flaking, burning or tingling in the areas of application.
- Allergic reactions: rarely – allergic dermatitis (more often associated with the reaction to auxiliary substances); In rare cases – angioedema.